BDBM557890 1-(4-((4-((3-cyclopropyl- phenyl)amino)-7-methoxy- quinazolin-6-yl)oxy)- piperidin-1-yl)prop-2-en-1- one::US11365189, Ex. No. 28
SMILES COc1cc2ncnc(Nc3cccc(c3)C3CC3)c2cc1OC1CCN(CC1)C(=O)C=C
InChI Key InChIKey=QFRBSGJSBTVAMI-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 557890
TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Homo sapiens (Human))
Board of Regents, The University of Texas System
US Patent
Board of Regents, The University of Texas System
US Patent
Affinity DataIC50: 410nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair